The premise will be something along the lines of a sexy female researcher (Debbie Gibson and Tiffany seem to be busy making Mega Python v. Gatoroid, my vote: Monica) doing experiments on some non-specific disease spread by mosquitoes. Then something goes horribly wrong and the mosquitoes are accidentally injected with some huge growth DNA, start growing at a monumental pace, and bust out to terrorize the locals.

Surprisingly there are not many pictures of Monica wearing nerd glasses and a lab coat. But just picture her in front of a microscope, taking notes, and speaking very seriously about nucleotides and protein strands.
They megamosquitoes (gigantormosquitoes?) look like this, except about 2358 times bigger.

There will also have to be some secondary love plot with a sexy law enforcement official or maybe a CDC guy worried about diseases or an overzealous entomologist. It's still a work in progress but you get my drift. I think the ultimate showdown would be at a soccer match and there would be many scenes of angry soccer fans looking around wondering who the assholes with vuvuzelas are and then BAM! they'll look up and be attacked by gigantic mosquitoes!
I'll be accepting that emmy nomination any day now.